Publications

Immune Senescence Project

• Freeman SL, Fisher L, German JB, Leung PS, Prince H, Selmi C, Naguwa SM, Gershwin ME. Dairy proteins and the response to pneumovax in senior citizens: a randomized, double-blind, placebo-controlled pilot study. Ann NY Acad Sci 2010; 1190: 97-103.

Bovine Genomics Project

• Wickramasinghe S, Hua S, Rincon G, Islas-Trejo A, German JB, Lebrilla CB, Medrano JF. Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing. PLoS One. 2011 Apr 25;6(4):e18895.
• Lemay DG, Rijnkels M, German JB, Lessons from the bovine genome: implications for human nutrition and research, Nutr. 2009 Jul;139(7):1271-2.
• Bovine Genome Sequencing and Analysis Consortium, Elsik CG, Tellam RL, et al, The genome sequence of taurine cattle: a window to ruminant biology and evolution, Science. 2009 Apr 24;324(5926):522-8.
• Tellam RL, Lemay DG, Van Tassell CP, Lewin HA, Worley KC, Elsik CG. Unlocking the bovine genome. BMC Genomics. 2009 Apr 24;10:193.
• Lemay DG, Lynn DJ, Martin W, et al, The bovine lactation genome: insights into the evolution of mammalian milk, Genome Biol. 2009;10(4):R43. 

Skin Lipids Project

• Coming soon...
  

Bioactives from Whey Processing

• Zivkovic AM, Barile D. Bovine milk as a source of functional oligosaccharides for improving human health. Adv Nutr. 2011 May;2(3):284-9.
  
• Barile D, Marotta M, Chu C, Mehra R, Grimm R, Lebrilla CB, German JB. Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. J. Dairy Sci. 2010; 93: 3940-3949.
• Barile D, Tao N, Lebrilla CB, Coisson JD, Arlorio M, German JB. Permeate from cheese whey ultrafiltration is a source of milk oligosaccharides. Int Dairy J 2009;19:524-530.

Milk Protein Phosphorylation Project

• Froehlich JW, Chu CS, Tang N, Waddell K, Grimm R, Lebrilla CB. Label-free liquid chromatography-tandem mass spectrometry analysis with automated phosphopeptide enrichment reveals dynamic human milk protein phosphorylation during lactation. Anal Biochem. 2011 Jan 1;408(1):136-46.

Lactosome Biology Project

• Argov-Argaman N, Smilowitz JT, Bricarello DB, Barboza M, Lerno L, Froehlich J, Lee H, Zivkovic AM, Lemay DG, Freeman S, Lebrilla CB, Parikh A, German JB, Lactosomes: structural and compositional classification of unique nanometer-sized protein lipid particles of human milk, J Agric Food Chem, 2010 Oct 6 [Epub ahead of print].
• Argov N, Wachsmann-Hogiu S, Freeman SL, Huser T, Lebrilla CB, German JB. Size-dependent lipid content in human milk fat globules. J Agric Food Chem. 2008 Aug 27;56(16):7446-50.

Bovine Milk Oligosaccharides Project

• Sundekilde UK, Barile D, Meyrand M, Poulsen NA, Larsen LB, Lebrilla CB, German JB, Bertram HC. Natural variability in bovine milk oligosaccharides from Danish Jersey and Holstein-Friesian breeds.  J Agric Food Chem. 2012 Jun 20;60(24):6188-96.
• Zivkovic AM, Barile D. Bovine milk as a source of functional oligosaccharides for improving human health. Adv Nutr. 2011 May;2(3):284-9.
• Wu S, Grimm R, German JB, Lebrilla CB. Annotation and structural analysis of sialylated human milk oligosaccharides. J Proteome Res. 2011 Feb 4;10(2):856-68.
• Tao N, Wu S, Kim J, An HJ, Hinde K, Power ML, Gagneux P, German JB, Lebrilla CB. Evolutionary Glycomics: Characterization of Milk Oligosaccharides in Primates. J Proteome Res. J Proteome Res. 2011 Apr 1;10(4):1548-57.
• Barile D, Marotta M, Chu C, Mehra R, Grimm R, Lebrilla CB, German JB. Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. J. Dairy Sci. 2010; 93: 3940-3949.
• Zivkovic AM, German JB, Lebrilla CB, Mills DA. Microbes and Health Sackler Colloquium: Human milk glycobiome and its impact on the infant gastrointestinal microbiota. Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4653-8.
• Sela DA, Mills DA. Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides. Trends Microbiol. 2010 Jul;18(7):298-307.
• Wu S, Tao N, German JB, Grimm R, Lebrilla CB. The development of an annotated library of neutral human milk oligosaccharides. J Proteome Res. 2010 Aug 6;9(8):4138-51.
• Marcobal A, Barboza M, Froehlich JW, Block, D., German, J.B., Lebrilla, C.B., Mills, D.A. Consumption of Human Milk Oligosaccharides by Gut-Related Microbes. J Agric Food Chem 2010; 58(9): 5334-40.
• Tao N, DePeters EJ, German JB, Grimm R, Lebrilla CB. Variations in bovine milk oligosaccharides during early and middle lactation stages analyzed by high-performance liquid chromatography-chip/mass spectrometry. J Dairy Sci 2009; 92:2991-3001.
• Dodds, E. D., R. R. Seipert, et al. (2009). "Analytical performance of immobilized pronase for glycopeptide footprinting and implications for surpassing reductionist glycoproteomics." J Proteome Res 8(2): 502-12.
• Niñonuevo MR, Lebrilla CB. Mass spectrometric methods for analysis of oligosaccharides in human milk. Nutr Rev. 2009 Nov;67 Suppl 2:S216-26.
• Barile D, Tao N, Lebrilla CB, Coisson JD, Arlorio M, German JB. Permeate from cheese whey ultrafiltration is a source of milk oligosaccharides. Int Dairy J 2009;19:524-530.
• Barboza M, Sela DA, Pirim C, et al. Glycoprofiling bifidobacterial consumption of galacto-oligosaccharides by mass spectrometry reveals strain-specific, preferential consumption of glycans. Appl Environ Microbiol 2009;75:7319-25. 
• Sela, D. A., J. Chapman, et al. (2008). "The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome." Proc Natl Acad Sci U S A 105(48): 18964-9.
• Tao N, DePeters EJ, Freeman S, German JB, Grimm R, Lebrilla CB. Bovine milk glycome. J Dairy Sci 2008;91:3768-78.
• Seipert, R. R., E. D. Dodds, et al. (2008). "Factors that influence fragmentation behavior of N-linked glycopeptide ions." Anal Chem 80(10): 3684-92.
• Ninonuevo, M. R., P. D. Perkins, et al. (2008). "Daily variations in oligosaccharides of human milk determined by microfluidic chips and mass spectrometry." J Agric Food Chem 56(2): 618-26.
• LoCascio, R. G., M. R. Ninonuevo, et al. (2007). "Glycoprofiling of bifidobacterial consumption of human milk oligosaccharides demonstrates strain specific, preferential consumption of small chain glycans secreted in early human lactation." J Agric Food Chem 55(22): 8914-9.
• Dodds, E. D., J. B. German, et al. (2007). "Enabling MALDI-FTICR-MS/MS for high-performance proteomics through combination of infrared and collisional activation." Anal Chem 79(24): 9547-56.
• Ward, R. E., M. Ninonuevo, et al. (2007). "In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria." Mol Nutr Food Res 51(11): 1398-405.

Comparative Lactation Project

• Hinde K, German JB. Food in an evolutionary context: insights from mother's milk. J Sci Food Agric. 2012 Aug 30;92(11):2219-23.
  
• Tao N, Wu S, Kim J, An HJ, Hinde K, Power ML, Gagneux P, German JB, Lebrilla CB. Evolutionary Glycomics: Characterization of Milk Oligosaccharides in Primates. J Proteome Res. J Proteome Res. 2011 Apr 1;10(4):1548-57.
• Hinde, K., Capitanio, JP. (2010) Lactational programming? Mother's milk predicts infant temperament and behavior. Am J Primatol Jun;72(6):522-9.
• Hinde, K. (2009) Richer milk for sons but more milk for daughters: sex biased investment during lactation varies with maternal life history in rhesus macaques. Am J Hum Biol 21:512-519.
• Hinde, K., M. Power, and O. Oftedal, (2009) Rhesus macaque milk: Magnitude, sources, and consequences of individual variation over lactation. Am J Phys Anth. 138:148-57.
• Hinde, K., (2007) Milk composition varies in relation to the presence and abundance of Balantidium coli in the mother in captive rhesus macaques (Macaca mulatta). Am J Primatol 69:625-634.
• Hinde, K., (2007) First-time macaque mothers bias milk composition in favor of sons. Current Biology 17: R958-R959.

Gates Foundation Milk and Microbiome Project

• Gordon JI, Dewey KG, Mills DA, Medzhitov RM. The human gut microbiota and undernutrition. Sci Transl Med. 2012 Jun 6;4(137):137ps12.